<i>C</i> ₁ ‐Symmetric Atropisomeric NHC Palladium(II) Complexes: Synthesis, Resolution and Characterization

Series of chiral palladium(II) allyl and cinnamyl complexes bearing a C1-symmetric N-heterocyclic carbenes were synthesized from achiral precursors. The chirality theses results the formation carbene-palladium bond which restricts rotation dissymmetric N-aryl substituents NHC thus creates an axis chirality. Chiral HPLC at preparative scale enabled resolution racemic provided straightforward access to with excellent enantiopurities (>99.5% ee). Enantiopure studied by crystal X-ray diffraction electronic circular dichroism (ECD). Their configuration stabilities investigated both experimentally theoretically through determination rotational barrier values. These tested for intramolecular α-arylation amides, moderate induction (up 54%